New Alkaloids from Hippeastrum papilio (Ravenna) Van Scheepen

GUO, Y.; DE ANDRADE, J.P.; PIGNI, N.B.; TORRAS-CLAVERIA, L.; TALLINI, L.R.; DE SOUZA BORGES, W.; VILADOMAT, F.; NAIR, J.J.; ZUANAZZI, J.A.S.; BASTIDA, J.

HELVETICA CHIMICA ACTA

WILEY-V C H VERLAG GMBH

Lugar: Weinheim; Año: 2016 vol. 99 p. 143 - 143

0018-019X

new phytochemical study of the indigenous Brazilian species Hippeastrum papilio is reported herein. Three novel Amaryllidaceae alkaloids were isolated, including hippapiline (1), papiline (2), and 3-O-demethyl-3-O-(3-hydroxybutanoyl)haemanthamine (3). Their structures were determined by physical and spectroscopic methods. In addition, the known alkaloids, haemanthamine (4), galanthamine (5), narwedine (6), 11β-hydroxygalanthamine (7), apogalanthamine (8), and 9-O-demethyllycosinine B (9) were identified. The unusual cis-B/C-ring fusion for the new homolycorine representative hippapiline was ratified by NMR and CD spectroscopy.